Gene Expression in Neutrophil-like Cell Lines

Expression data is for primary human and murine neutrophils and PLB985 or HL60 cells before and after differentiation with either 1.3% DMSO or 1.3% DMSO + 0.5% Nutridoma-CS (Sigma). Expression values are FPKM normalized on a log10 scale. Transcripts that were undetected were assigned an arbitrary value of -4.00. Data for PLB985 and HL60 cells is our own RNA-Seq data. Raw data for primary human and mouse neutrophils was collated from previously published studies and analyzed along-side our own1-6. For convenience, links to Dictyostelium discoideum homologs are also displayed. 

For more information, see:
Rincon E., Rocha-Gregg B. & Collins S. A map of gene expression in neutrophil-like cell lines. 2018.
Pre-print available on bioRxiv

Data may be searched by symbol, Gene ID or protein domain and sorted by any column. Users can choose to display a subset of columns by selecting columns from the upper right hand side of the database. Use the icons to print or export the data as desired.

Gene Expression in Neutrophil-like Cell Lines

Symbol GeneID Primary Human PLB985 Undiff PLB985 +DMSO PLB985 +Nutri HL60 Undiff HL60 +DMSO HL60 +Nutri Mouse_Homolog Mouse Dicty_Homolog Prot_Domain
TSPAN6 7105 -2.18 -4.00 -4.00 -4.00 -4.00 -4.00 -4.00 Tspan6 -0.91 - 4HB_MCP_1|Tetraspannin
TNMD 64102 -4.00 -4.00 -4.00 -4.00 -4.00 -4.00 -4.00 Tnmd -4.00 - BRICHOS
DPM1 8813 1.41 1.72 1.58 1.57 1.75 1.55 1.60 Dpm1 0.75 dgtB Glyco_tranf_2_2|Glyco_tranf_2_3|Glyco_transf_21|Glycos_transf_2
SCYL3 57147 0.76 0.34 0.54 0.55 0.25 0.45 0.40 Scyl3 1.02 - Pkinase|Pkinase_Tyr
C1orf112 55732 0.40 0.97 0.18 0.26 0.77 0.03 0.20 BC055324 0.28 - DUF4487|Sec23_helical
FGR 2268 2.73 0.02 0.51 0.89 0.79 1.44 1.34 Fgr 2.31 - Pkinase|Pkinase_Tyr|SH2|SH3_1|SH3_2|SH3_9
CFH 3075 -1.09 -4.00 -4.00 -4.00 -4.00 -4.00 -2.20 Cfh 0.07 - Sushi
FUCA2 2519 0.49 -2.54 -4.00 -2.74 0.57 0.52 0.85 Fuca2 1.71 - Alpha_L_fucos|Fucosidase_C
GCLC 2729 0.61 1.51 1.63 1.49 1.46 1.64 1.70 Gclc 0.25 gcsA GCS
NFYA 4800 1.50 1.05 1.09 1.16 0.93 0.98 1.14 Nfya 1.23 - CBFB_NFYA
Symbol GeneID Primary Human PLB985 Undiff PLB985 +DMSO PLB985 +Nutri HL60 Undiff HL60 +DMSO HL60 +Nutri Mouse_Homolog Mouse Dicty_Homolog Prot_Domain

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